Abstract: The neural controls of human and animal locomotion have been studied over centuries. However, much of our knowledge about the control of complex species, especially humans, still relies on extrapolating from what is known in simpler animals. Simulation studies of testing different control hypotheses may help better understanding the control. In this seminar, I present a neuromuscular model of human locomotion that can generate diverse locomotion behaviors including walking and running, acceleration and deceleration, slope and stair negotiation, turning, and deliberate obstacle avoidance. In addition, will be presented how the proposed model can be used in designing and testing robotic assistive devices.